Chiral nanoporous metal–metallosalen frameworks for hydrolytic kinetic resolution of epoxides

C Zhu, G Yuan, X Chen, Z Yang…

Index: Zhu, Chengfeng; Yuan, Guozan; Chen, Xu; Yang, Zhiwei; Cui, Yong Journal of the American Chemical Society, 2012 , vol. 134, # 19 p. 8058 - 8061

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Citation Number: 132

Abstract

Chiral nanoporous metal–organic frameworks are constructed by using dicarboxyl- functionalized chiral Ni (salen) and Co (salen) ligands. The Co (salen)-based framework is shown to be an efficient and recyclable heterogeneous catalyst for hydrolytic kinetic resolution (HKR) of racemic epoxides with up to 99.5% ee. The MOF structure brings Co (salen) units into a highly dense arrangement and close proximity that enhances ...