The Journal of Organic Chemistry

Synthesis of. alpha.-and. beta.-nicotyrines. Use of phenyl vinyl sulfoxide as a masked equivalent of acetylene dipolarophile

GB Mullen, VS Georgiev

Index: Mullen, George B.; Georgiev, Vassil St. Journal of Organic Chemistry, 1989 , vol. 54, # 10 p. 2476 - 2478

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Citation Number: 11

Abstract

Presently available pro~ edures”'~ for the preparation of/3-nicotyrine utilize only nicotine as starting material and are handicapped by either low yields or the necessity of using harsh experimental conditions (temperatures of over 300 “C in sealed or electrically heated reaction vessels). Such conditions would undoubtedly limit the scale of the synthesis. Therefore, new methods for the preparation of P-nicotyrine continue to be of interest, ...