Ruthenium??Catalyzed Nitro and Nitrile Compounds Coupling with Alcohols: Alternative Route for N??Substituted Amine Synthesis

X Cui, Y Zhang, F Shi, Y Deng

Index: Cui, Xinjiang; Zhang, Yan; Shi, Feng; Deng, Youquan Chemistry - A European Journal, 2011 , vol. 17, # 9 p. 2587 - 2591

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Citation Number: 44

Abstract

Amines and their derivatives play critical roles as building blocks, functional linkages, and key moieties in peptides, polymers, and many natural products and pharmaceuticals. In addition, a plenty of naturally and man-made bioactive compounds, such as amino acids, nucleic acids, and enzymes, contain N-substituted amines.[1] N-Substituted amines are usually prepared by the alkylation of amines with halides.[2] However, this method is ...