Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity

C Changtam, P Hongmanee, A Suksamrarn

Index: European Journal of Medicinal Chemistry, , vol. 45, # 10 p. 4446 - 4457

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Citation Number: 73

Abstract

... European Journal of Medicinal Chemistry. ... However, the well known medicinal use of curcuminoids, the relatively less toxicity of these food ingredients and the unlimited availability of the ... Reagents and conditions: (j) p-TsOH, C 6 H 6 , reflux; (k) DDQ, THF; (l) H 2 /Pd–C, EtOH. ...