Tetrahedron letters

An improved protocol for ligandless Suzuki–Miyaura coupling in water

DN Korolev, NA Bumagin

Index: Korolev, Dmitrii N.; Bumagin, Nikolay A. Tetrahedron Letters, 2006 , vol. 47, # 25 p. 4225 - 4229

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Citation Number: 55

Abstract

Using a reverse order of addition of reagents, PdCl2 and Pd (OAc) 2 are efficient catalysts for the Suzuki–Miyaura reactions in water. The ligandless and mild conditions, the high stability of the catalytic system, short reaction time and good to excellent yields are important features of this protocol.