The synthesis and pharmacological actions of ortho-substituted phenethylhydrazines

EL Schumann, ME Greig…

Index: Schumann,E.L. et al. Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 3, p. 567 - 582

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Citation Number: 10

Abstract

Substances related to amphetamine have been known for some time to cause inhibition of monoamine oxidase (MAO). It was found, in our laboratories, that o-methoxy-a- methylphenethyl-methylamine hydrochloride* was a moderately good MA0 inhibitor, Recently, a-methylphenethylhydrazinet (JB-5 16) was reportedlt 2 to be a very potent inhibitor of this enzyme. The present series of compounds, also related to amphetamine ...