O-Hetaryl substituted carbohydrates and their neurotropic activity

NN Karkishchenko, VG Alekseev, VA Anisimova…

Index: Karkishchenko, N. N.; Alekseev, V. G.; Anisimova, V. A.; Korol', E. L.; Vilkov, G. A.; et al. Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 4 p. 242 - 247 Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 4 p. 408 - 413

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Abstract

N-and C-substituted monosaccharides, incluing their hetaryl derivatives, have found rather extensive application in clinlcal practlce as inhlbltors of nucleic acldmetabollsmwlth anticancer, antivirus, and immunodepressant activity [16]. C-Hetaryl-substituted carbohydrates [5], among which derivatives with anticoagulant [6], antimicrobial [8], and neurotropic activity [8] have been discovered, are of particular interest as a consequence ...