e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Design, synthesis, and structure–activity relationship studies of conformationally restricted mutilin 14-carbamates

L Fu, X Liu, C Ling, J Cheng, X Guo, H He…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 2 p. 814 - 819

Full Text: HTML

Citation Number: 12

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... In this letter, we reported the design, synthesis, and SAR of a series of novel conformationally restricted mutilin 14-carbamates. ...

Methyl 2-methyl-5-fluorobenzoate Structure

Methyl 2-methyl...

~%

6-Fluoro-1-isoindolinone Structure

6-Fluoro-1-isoi...

Methyl 2-(Bromomethyl)-5-Fluorobenzoate Structure

Methyl 2-(Bromo...

~%

6-Fluoro-1-isoindolinone Structure

6-Fluoro-1-isoi...

Methyl 2-methyl-5-nitrobenzoate Structure

Methyl 2-methyl...

~%

6-Nitroisoindolin-1-one Structure

6-Nitroisoindol...

Methyl 2-(bromomethyl)-5-nitrobenzoate Structure

Methyl 2-(bromo...

~%

6-Nitroisoindolin-1-one Structure

6-Nitroisoindol...

Ethyl 3-Methoxyphenethylcarbamate Structure

Ethyl 3-Methoxy...

~%

6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one Structure

6-Hydroxy-3,4-d...

3-Methoxy-2-phenylethylamine Structure

3-Methoxy-2-phe...

~%

6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one Structure

6-Hydroxy-3,4-d...

5-Bromo-2,3-dihydroisoindol-1-one Structure

5-Bromo-2,3-dih...

~%

5-Aminoisoindolin-1-one Structure

5-Aminoisoindol...

N/A Structure

~%

5-Aminoisoindolin-1-one Structure

5-Aminoisoindol...

2-Phenylethanamine Structure

2-Phenylethanamine

~%

7-NITRO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE Structure

7-NITRO-3,4-DIH...

Ethyl phenethylcarbamate Structure

Ethyl phenethyl...

~%

7-NITRO-3,4-DIHYDRO-2H-ISOQUINOLIN-1-ONE Structure

7-NITRO-3,4-DIH...

Methyl 3-methoxy-2-methylbenzoate Structure

Methyl 3-methox...

~%

4-Methoxyisoindolin-1-one Structure

4-Methoxyisoind...

Design, synthesis, and structure–activity relationship studi...

[Fu, Liqiang; Liu, Xin; Ling, Chenyu; Cheng, Jianjun; Guo, Xingsheng; He, Huili; Ding, Shi; Yang, Yushe Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 814 - 819]

Design, synthesis, and structure–activity relationship studi...

[Fu, Liqiang; Liu, Xin; Ling, Chenyu; Cheng, Jianjun; Guo, Xingsheng; He, Huili; Ding, Shi; Yang, Yushe Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 2 p. 814 - 819]