Copper??Catalyzed Tandem C N Bond Formation: An Efficient Annulative Synthesis of Functionalized Cinnolines

CJ Ball, J Gilmore, MC Willis

Index: Ball, Catherine J.; Gilmore, Jeremy; Willis, Michael C. Angewandte Chemie - International Edition, 2012 , vol. 51, # 23 p. 5718 - 5722

Full Text: HTML

Citation Number: 32

Abstract

Transition metal-catalyzed aryl CÀN bond formation [1] has become an important tool in the synthesis of heterocycles.[2] Mild conditions, readily accessible starting materials and userfriendly procedures are among the advantages that such a strategy offers compared to classical syntheses. However, the development of general and flexible routes to a wider variety of heterocycles remains an important goal. Cinnolines, and cinnoline derivatives, ...