Tetrahedron

One-pot synthesis of highly substituted indolines

KG Liu, JR Lo, AJ Robichaud

Index: Liu, Kevin G.; Lo, Jennifer R.; Robichaud, Albert J. Tetrahedron, 2010 , vol. 66, # 3 p. 573 - 577

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Citation Number: 10

Abstract

A general and convenient one-pot synthesis of highly substituted indolines from arylhydrazines and aldehydes is reported. This synthesis allows introduction of substitution at essentially all positions of the indoline nucleus to achieve significant diversity in this biologically important template.