e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
A Convenient Method for Introducing Oxo Group into the. BETA.-Position of Cyclic Amines and Its Application to Synthesis of. DELTA.-Aminolevulinic Acid.
Y Matsumura, Y Takeshima, H Okita
Index: Matsumura; Takeshima; Okita Bulletin of the Chemical Society of Japan, 1994 , vol. 67, # 1 p. 304 - 306
Oxo group could be introduced into the β-position of N-methoxycarbonylated cyclic amines by utilizing electrochemical oxidation and/or m-chloroperbenzoic acid oxidation, and this method was applied to the preparation of δ-aminolevulinic acid, an intermediate of chlorophyll biosynthesis.