Tetrahedron Letters

A Direct Method for the Substitution of Imidazo [1, 5-a] pyridines at Position 5

P Blatcher, D Middlemiss

Index: Blatcher, Philip; Middlemiss, David Tetrahedron Letters, 1980 , vol. 21, p. 2195 - 2196

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Citation Number: 15

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 3-Ethylthioimidazo[1,5-a]pyridine lithiates at carbon 5. Quenching of the anion with an electrophile followed by desulphurisation gives 5-substituted imidazo[1,5-a]pyridines. ... Imidazo[1,5-a]pyridines with substituents in the 6-membered ring can be prepared from the appropriate pyridine ...