Synthesis of 2-and 2, 3-substituted pyrazolo [1, 5-a] pyridines: scope and mechanistic considerations of a domino direct alkynylation and cyclization of N- …

JJ Mousseau, JA Bull, CL Ladd, A Fortier…

Index: Miki, Yasuyoshi; Tasaka, Junko; Uemura, Kyoko; Miyazeki, Kunihiro; Yamada, Jun Heterocycles, 1996 , vol. 43, # 10 p. 2249 - 2256

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Citation Number: 46

Abstract

... Volume: Page ... than 90% of molecules currently under investigation by pharmaceutical companies contain nitrogen heterocycles, and of ... range of inexpensive phosphine reagents providing comparable levels of conversion to the desired heterocycle, displaying a ...

Phosphodiesterase inhibitors. Part 4: Design, synthesis and ...

[Ochiai, Koji; Takita, Satoshi; Kojima, Akihiko; Eiraku, Tomohiko; Ando, Naoki; Iwase, Kazuhiko; Kishi, Tetsuya; Ohinata, Akira; Yageta, Yuichi; Yasue, Tokutaro; Adams, David R.; Kohno, Yasushi Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 18 p. 5833 - 5838]