Tetrahedron letters

An asymmetric synthesis of sulfobacin A

A Sharma, S Gamre, S Chattopadhyay

Index: Sharma, Anubha; Gamre, Sunita; Chattopadhyay, Subrata Tetrahedron Letters, 2007 , vol. 48, # 21 p. 3705 - 3707

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Citation Number: 12

Abstract

A facile synthesis of sulfobacin A has been developed starting from (R)- cyclohexylideneglyceraldehyde (11). The key steps in the synthesis are the highly diastereocontrolled allylation of 11 and syn-selective reduction of a ketone derived from 11. The other attractive features are the operational simplicity and the use of inexpensive compounds/reagents.