Tetrahedron

The biosynthesis of the alkaloids of Cissampelos pareira Linn

DS Bhakuni, S Jain, R Chaturvedi

Index: Bhakuni,Dewan S.; Jain,Sudha; Chaturvedi,Rekha Tetrahedron, 1987 , vol. 43, # 17 p. 3975 - 3982

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Citation Number: 12

Abstract

Tracer experiments show that the bisbenzylisoquinoline alkaloid,(S, R)-hayatidin (10) is stereospecifically biosynthesized in young Cissampelos pareira Linn plants by intermolecular oxidative coupling of (S)-(5)-and (R)-(3), N-methylcoclaurines whereas (R, R)- isochondrodendrine (14) and (R, R)-bebeerine (12) are formed in the plants by oxidative dimerization of (R)-N-methylcoclaurine (3).