Poly (squaramides) are a novel class of anion-responsive macromolecules that incorporate the diaminocyclobutenedione hydrogen bond donor group into the polymer backbone. Herein, the synthesis and properties of a series of fluorene-based poly (squaramides) varying in conformational rigidity, squaramide content, and propensity for aggregation are described. Structure–activity relationships for the anion sensory behavior of these ...