Journal of the American Chemical Society

Alkylations with substituted furfurylamines

EL Eliel, PE Peckham

Index: Eliel; Peckham Journal of the American Chemical Society, 1950 , vol. 72, p. 1209,1210

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Citation Number: 25

Abstract

It has been known for some time that alkylations with tertiary amines of the type RCHzN- (CH3) z and their quaternary salts proceed much inore readily when R is 2-pyrryI2 (11) or 3- indoly13 (111) than when R is phenyl4 (I). The hypothesis that the enhanced reactivity of the heterocyclic amines is due to the operation of an elimination-addition mechanism5 is inadequate, since 1-methylgramine (IV) which cannot react by such a mechanism also ...