The Journal of organic chemistry

AlCl3⊙ 6H2O/KI/H2O/CH3CN: A New Alternate System for Dehydration of Oximes and Amides in Hydrated Media

M Boruah, D Konwar

Index: Boruah, Monalisa; Konwar, Dilip Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 7138 - 7139

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Citation Number: 66

Abstract

Dehydration of oximes and amides to nitriles was carried out using the AlCl3⊙ 6H2O/KI/H2O/CH3CN system. It produced isoquinoline derivatives 8a-c (Bischler Naperialski reaction) when reacted with amides 7a-c in hydrated media. Also, the keto oximes produced anilides (Beckmann rearrangement) with the system under the same reaction conditions.

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