Improved Synthesis of γ-Lactones from Cyclopropyl Cyanoesters

NC Patel, JB Schwarz, K Islam, W Miller…

Index: Patel, Nandini C.; Schwarz, Jacob B.; Islam, Khondaker; Miller, Whitney; Tran, Tuan P.; Wei, Yunjing Synthetic Communications, 2011 , vol. 41, # 15 p. 2209 - 2215

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Abstract

View all references ] During the course of an effort directed toward the preparation and biological testing of a series of cyclopropyl β-amino acids 3, we relied on the use of cyanoester intermediates 2. [ 2 2. Schwarz , JB ; Gibbons , SE ; Graham , SR ; Colbry , NL ; Guzzo , PR ; Le , V.-D. ; Vartanian , MG ; Kinsora , JJ ; Lotarski , SM ; Li , Z. ; Dickerson , MR ; Su , T.-Z. ; Weber , ML ; El-Kattan , A. ; Thorpe , AJ ; Donevan , SD ; Taylor , CP ; Wustrow , DJ Novel cyclopropyl β-amino ...