Discovery of an N-(2-aminopyridin-4-ylmethyl) nicotinamide derivative: a potent and orally bioavailable NCX inhibitor

T Kuramochi, A Kakefuda, H Yamada…

Index: Bioorganic and Medicinal Chemistry, , vol. 13, # 12 p. 4022 - 4036

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Citation Number: 16

Abstract

... JavaScript is disabled on your browser. Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. Volume 13, Issue 12, 2 June 2005, Pages 4022–4036. Cover image Cover image. ... 2. Chemistry. ...

 Related Synthetic Route
2-Chloronicotinic acid Structure

6313-54-8

2-Chloronicotin...

~%

Methyl 2-(Boc-amino)isonicotinate Structure

639091-75-1

Methyl 2-(Boc-a...

2-Chloronicotinic acid Structure

6313-54-8

2-Chloronicotin...

~%

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Structure

89937-77-9

Methyl 1,2-dihy...

2-Methoxyisonicotinic acid Structure

105596-63-2

2-Methoxyisonic...

~%

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Structure

89937-77-9

Methyl 1,2-dihy...

Methanol Structure

67-56-1

Methanol

2-amino-4-carboxypyridine Structure

13362-28-2

2-amino-4-carbo...

~%

Methyl 2-aMinopyridine-4-carboxylate Structure

6937-03-7

Methyl 2-aMinop...

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Structure

89937-77-9

Methyl 1,2-dihy...

2-(Boc-amino)-4-(hydroxymethyl)pyridine Structure

304873-62-9

2-(Boc-amino)-4...

~%

2-(Boc-amino)-4-(aminomethyl)pyridine Structure

639091-78-4

2-(Boc-amino)-4...

Methyl 2-(Boc-amino)isonicotinate Structure

639091-75-1

Methyl 2-(Boc-a...

~%

2-(Boc-amino)-4-(aminomethyl)pyridine Structure

639091-78-4

2-(Boc-amino)-4...

{2-[(tert-butoxycarbonyl)amino]pyridin-4-yl}methyl methanesulfonate Structure

639091-76-2

{2-[(tert-butox...

~%

2-(Boc-amino)-4-(aminomethyl)pyridine Structure

639091-78-4

2-(Boc-amino)-4...

2-Chloronicotinic acid Structure

6313-54-8

2-Chloronicotin...

~%

2-(Boc-amino)-4-(aminomethyl)pyridine Structure

639091-78-4

2-(Boc-amino)-4...

2-amino-4-carboxypyridine Structure

13362-28-2

2-amino-4-carbo...

~%

2-(Boc-amino)-4-(aminomethyl)pyridine Structure

639091-78-4

2-(Boc-amino)-4...

2-Chloronicotinic acid Structure

6313-54-8

2-Chloronicotin...

~%

Methyl 2-aMinopyridine-4-carboxylate Structure

6937-03-7

Methyl 2-aMinop...

Methanol Structure

67-56-1

Methanol

2-amino-4-carboxypyridine Structure

13362-28-2

2-amino-4-carbo...

~%

Methyl 2-aMinopyridine-4-carboxylate Structure

6937-03-7

Methyl 2-aMinop...

Methyl 1,2-dihydro-2-oxopyridine-4-carboxylate Structure

89937-77-9

Methyl 1,2-dihy...


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