Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept

A Kurimoto, K Hashimoto, T Nakamura…

Index: Journal of Medicinal Chemistry, , vol. 53, # 7 p. 2964 - 2972

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Citation Number: 49

Abstract

... Journal of Medicinal Chemistry. ... Chemistry Research II, Chemistry Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd., 3-1-98 Kasagade-naka, Konahana-ku, Osaka 554-0022, Japan. ‡ AstraZeneca R&D ...