Chemical Communications

Chemoenzymatic synthesis of GDP-azidodeoxymannoses: non-radioactive probes for mannosyltransferase activity

S Marchesan, D Macmillan

Index: Marchesan, Silvia; Macmillan, Derek Chemical Communications, 2008 , # 36 p. 4321 - 4323

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Citation Number: 12

Abstract

GDP-2-, 3-, 4-or 6-azidomannoses can be successfully prepared from the corresponding azidomannose-1-phosphates and GTP using the enzyme GDP-Mannosepyrophosphorylase (GDP-ManPP) from Salmonella enterica and may serve as useful probes for mannosyltransferase activity.

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