... J. Heterocyclic Chem., 31, 1381 (1994). ... and subsequent treat- ment of the crude alcohol with p-toluenesulfonic acid gives lactone 14 in a 69% combined yield (Scheme 3). Chemistry associated with ... [2] JI DeGraw, PH Christie, RL Kisliuk, Y. Gaumont and FM Sirotnak, J. Med. ...