Structural Optimization and Structure–Activity Relationships of N 2-(4-(4-Methylpiperazin-1-yl) phenyl)-N 8-phenyl-9 H-purine-2, 8-diamine Derivatives, a New Class of …

J Yang, LJ Wang, JJ Liu, L Zhong…

Index: Journal of Medicinal Chemistry, , vol. 55, # 23 p. 10685 - 10699

Full Text: HTML

Citation Number: 24

Abstract

... Journal of Medicinal Chemistry. ... State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, West China Medical School, Sichuan University, Sichuan 610041, China. ‡ West China School of Pharmacy ...

 Related Synthetic Route
N/A Structure

1414781-42-2

N/A

~%

4-bromo-2-fluorophenylisothiocyanate 96 Structure

81171-71-3

4-bromo-2-fluor...

4-Bromo-2-fluoroaniline Structure

367-24-8

4-Bromo-2-fluor...

~%

4-bromo-2-fluorophenylisothiocyanate 96 Structure

81171-71-3

4-bromo-2-fluor...

Structure

1414781-34-2

~%

3-Methylphenyl isothiocyanate Structure

621-30-7

3-Methylphenyl ...

N/A Structure

1414781-37-5

N/A

~%

3-chlorophenyl isothiocyanate Structure

2392-68-9

3-chlorophenyl ...

1,4-diazabicyclo[2.2.2]octane (4-bromophenyl)carbamodithioate Structure

1414781-39-7

1,4-diazabicycl...

~%

4-bromophenyl isothiocyanate Structure

1985-12-2

4-bromophenyl i...

1,4-diazabicyclo[2.2.2]octane (2,5-dichlorophenyl)carbamodithioate Structure

1414781-44-4

1,4-diazabicycl...

~%

2,5-dichlorophenyl isothiocyanate Structure

3386-42-3

2,5-dichlorophe...

2,5-Dichloroaniline Structure

95-82-9

2,5-Dichloroaniline

~%

2,5-dichlorophenyl isothiocyanate Structure

3386-42-3

2,5-dichlorophe...


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