Design, synthesis, biological evaluation, and structure–activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl) benzenesulfonates as new tubulin …

…, É Petitclerc, LP Kotra, R C.-Gaudreault

Index: Azim, El-Mostafa; Dupuy, Jean-Michel; Maurizis, Jean-Claude; C.-Gaudreault, Rene; Veyre, Annie; Madelmont, Jean-Claude Journal of Labelled Compounds and Radiopharmaceuticals, 1997 , vol. 39, # 7 p. 559 - 566

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Citation Number: 26

Abstract

Sixty-one phenyl 4-(2-oxoimidazolidin-1-yl) benzenesulfonates (PIB-SOs) and 13 of their tetrahydro-2-oxopyrimidin-1 (2 H)-yl analogues (PPB-SOs) were prepared and biologically evaluated. The antiproliferative activities of PIB-SOs on 16 cancer cell lines are in the