Abstract: Six ring-chlorinated derivatives of Ne-benzyloxycarbonyl-L-lysine were synthesized and their apparent first-order rates of deprotection in 50: 50 (v/v) trifluoroacetic acid-dichloromethane at 20" were quantitatively determined by ion-exchange chromatography. sec-9 follow in order of increasing stability: W-benzyloxycarbonyl-L-lysine (396)< Ne-(4-chlorobenzyloxycarbonyl)-~-lysine (1 38)<< W-(2-chlorobenzyloxycarbonyl)- ...
