Tetrahedron letters

BINOL-derived N-phosphino sulfoximines as ligands for asymmetric catalysis

MT Reetz, OG Bondarev, HJ Gais, C Bolm

Index: Reetz, Manfred T.; Bondarev, Oleg G.; Gais, Hans-Joachim; Bolm, Carsten Tetrahedron Letters, 2005 , vol. 46, # 34 p. 5643 - 5646

Full Text: HTML

Citation Number: 39

Abstract

BINOL-derived N-phosphino sulfoximines have been prepared for the first time and tested as ligands in asymmetric transition metal catalysis. Up to 99% ee was achieved in the Rh- catalyzed asymmetric hydrogenation of functionalized olefins and up to 66% ee in the Pd- catalyzed allylic alkylation.