Tetrahedron letters

An improved and practical procedure for the synthesis of substituted phenylacetylpyridines

M Journet, D Cai, RD Larsen, PJ Reider

Index: Journet, Michel; Cai, Dongwei; Larsen, Robert D.; Reider, Paul J. Tetrahedron Letters, 1998 , vol. 39, # 13 p. 1717 - 1720

Full Text: HTML

Citation Number: 14

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A general procedure for the synthesis of substituted phenylacetylpyridines in excellent yields is described using a Horner-Emmons condensation between α-aminoalkylphosphonates of pyridinecarboxaldehydes and benzaldehydes with cesium carbonate at room temperature. ... A general procedure ...

 Related Synthetic Route
N/A Structure

114444-27-8

N/A

~%

2-(3-Chlorophenyl)-1-(3-pyridinyl)-1-ethanone Structure

31251-55-5

2-(3-Chlorophen...

Nicotinaldehyde Structure

500-22-1

Nicotinaldehyde

~%

2-(3-Chlorophenyl)-1-(3-pyridinyl)-1-ethanone Structure

31251-55-5

2-(3-Chlorophen...

N-(diphenoxyphosphoryl-pyridin-3-yl-methyl)aniline Structure

3360-71-2

N-(diphenoxypho...

~%

2-(3-Chlorophenyl)-1-(3-pyridinyl)-1-ethanone Structure

31251-55-5

2-(3-Chlorophen...

N-(2-(4-chlorophenyl)-1-(pyridin-3-yl)vinyl)aniline Structure

114444-21-2

N-(2-(4-chlorop...

~%

2-(4-CHLOROPHENYL)-1-(PYRIDIN-3-YL)ETHANONE Structure

31251-54-4

2-(4-CHLOROPHEN...

Nicotinaldehyde Structure

500-22-1

Nicotinaldehyde

~%

2-(4-CHLOROPHENYL)-1-(PYRIDIN-3-YL)ETHANONE Structure

31251-54-4

2-(4-CHLOROPHEN...

N-(diphenoxyphosphoryl-pyridin-3-yl-methyl)aniline Structure

3360-71-2

N-(diphenoxypho...

~%

2-(4-CHLOROPHENYL)-1-(PYRIDIN-3-YL)ETHANONE Structure

31251-54-4

2-(4-CHLOROPHEN...

Nicotinaldehyde Structure

500-22-1

Nicotinaldehyde

~%

P-METHOXYBENZYL-(3-PYRIDYL)-KETONE Structure

23827-45-4

P-METHOXYBENZYL...

N-(diphenoxyphosphoryl-pyridin-3-yl-methyl)aniline Structure

3360-71-2

N-(diphenoxypho...

~%

P-METHOXYBENZYL-(3-PYRIDYL)-KETONE Structure

23827-45-4

P-METHOXYBENZYL...

p-Formylpyridine Structure

872-85-5

p-Formylpyridine

~%

2-PHENYL-1-(PYRIDIN-4-YL)ETHANONE Structure

1017-24-9

2-PHENYL-1-(PYR...

Nicotinaldehyde Structure

500-22-1

Nicotinaldehyde

DIPHENYL PHOSPHITE Structure

4712-55-4

DIPHENYL PHOSPHITE

Structure

74497-02-2

~86%

N-(diphenoxyphosphoryl-pyridin-3-yl-methyl)aniline Structure

3360-71-2

N-(diphenoxypho...

N-(2-(4-chlorophenyl)-1-(pyridin-4-yl)vinyl)aniline Structure

114443-86-6

N-(2-(4-chlorop...

~%

2-(4-chlorophenyl)-1-pyridin-4-ylethanone Structure

16273-84-0

2-(4-chlorophen...

p-Formylpyridine Structure

872-85-5

p-Formylpyridine

~%

2-(4-chlorophenyl)-1-pyridin-4-ylethanone Structure

16273-84-0

2-(4-chlorophen...


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