Synthesis of. alpha.-amino acids by alkylation of diethyl acetamidomalonate in the presence of palladium complexes

JP Haudegond, Y Chauvin…

Index: Journal of Organic Chemistry, , vol. 44, p. 3063 - 3065

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Citation Number: 49

Abstract

... The mixture was stirred at 100 "C for 4 h. After treatment with 10% aqueous KCN and extraction of the organic product with diethyl ether, the solvent was removed in vacuo to give 5 as a yellow oil (6.25 g, 32% yield): IR (neat) 3300, 3080, 1740, 1670, 885 cm ... J. Org. Chem., Vol. ...