The PdII-catalyzed asymmetric aza-Claisen rearrangement [1] of allylic trihaloacetimidates [2, 3] enables the transformation of achiral linear allylic alcohols to chiral enantioenriched allylic trihaloacetamides, precursors of chiral allylic amines. Recent studies with planar chiral pentaphenyl ferrocene palladacycles have helped to gain a more detailed understanding of the origin of enantioselectivity for this reaction type.[2e] These ...
