Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues

JA Nieman, JE Coleman, DJ Wallace…

Index: Journal of Natural Products, , vol. 66, # 2 p. 183 - 199

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Citation Number: 90

Abstract

... Journal of Natural ... in nM) versus antimitotic activity (IC 50 in nM) against human breast cancer MCF-7 mup53 cells for natural hemiasterlins, criamides ... activity versus IC 50 for cytotoxic activity against MCF-7 mup53 cells (Figure 1) for each of the naturally occurring hemiasterlins ...