Synthesis of salicylaldehydes bearing bulky substituents in the positions 3 and 5

AI Kochnev, II Oleynik, IV Oleynik, SS Ivanchev…

Index: Kochnev; Oleynik; Ivanchev; Tolstikov Russian Chemical Bulletin, 2007 , vol. 56, # 6 p. 1125 - 1129

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Citation Number: 17

Abstract

Abstract Reaction of 2, 4-disubstituted phenols with paraformaldehyde in the presence of SnCl 4 and 2, 6-lutidine afforded a number of new salicylaldehydes, containing bulky substituents (tert-butyl, 1-phenylethyl, 1-(4-tert-butylphenyl) ethyl, α-cumyl, and trityl) in the positions 3 and 5.