The efficacy of many pharmaceuticals and agrochemicals is oftcm enhanced or is dependent on the presence of a single fluorine atom in the structure.' Frequently, such compounds are synthesised from sn taller molecules in which fluorine is located at \pecific sites. Elemental fluorine is normally regarded as being too reactive for site specific fluorination reactions and many fluorinating a Sents have been developed in order to make desirable fluorine containing 'building ...
[Chambers, Richard D.; Hutchinson, John; Batsanov, Andrei S.; Lehmann, Christian W.; Naumov, Dimitrii Y. Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 18 p. 2271 - 2275]
