The synthesis and binding properties of a cyclodextrin tetramer are described. This species is composed of four individual cyclodextrin subunits covalently appended to a central aromatic core. The tetramer is prepared from P-cyclodextrin in five steps in an overall 14% yield. We have performed a preliminary survey of the binding properties of this species. The structure of tetramertetraarylporphryin complexes was examined by both NMR and mass ...