Chemical Communications

A new efficient synthesis of pyridines

ND Kimpe

Index: De Kimpe, Norbert; Keppens, Marian; Fonck, Gwendolien Chemical Communications, 1996 , # 5 p. 635 - 636

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Citation Number: 21

Abstract

Cyclic six-membered imines, ie 2, 3, 4, 5-tetrahydropyridines, are efficiently converted under mild conditions into the corresponding pyridines by highly regioselective α, α-dichlorination with N-chlorosuccinimide (NCS) followed by double dehydrochlorination with methanolic

~75%

~90%

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