Discovery of 2-amino-6-carboxamidobenzothiazoles as potent Lck inhibitors

S Huang, Z Liu, SS Tian, M Sandberg…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 7 p. 2324 - 2328

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Citation Number: 6

Abstract

... Bioorganic & Medicinal Chemistry Letters. Volume 18, Issue 7, 1 April 2008, Pages 2324–2328. ... By similar chemistry in Scheme 1, compounds 21 and 22 were synthesized, both of which exhibited several fold lower cellular potency relative to their corresponding analogues 4b ...