Evolution of a highly selective and potent 2-(pyridin-2-yl)-1, 3, 5-triazine Tie-2 kinase inhibitor

BL Hodous, SD Geuns-Meyer, PE Hughes…

Index: Journal of Medicinal Chemistry, , vol. 50, # 4 p. 611 - 626

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Citation Number: 87

Abstract

... Journal of Medicinal ... Departments of Medicinal Chemistry, Molecular Pharmacology, and Molecular Structure, Amgen Inc., One Kendall Square, Building 1000 ... 626. DOI: 10.1021/jm061107l. Publication Date (Web): January 25, 2007. Copyright © 2007 American Chemical Society. ...