Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor α

BB Busch, WC Stevens, R Martin…

Index: Journal of Medicinal Chemistry, , vol. 47, # 23 p. 5593 - 5596

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Citation Number: 96

Abstract

... Journal of Medicinal ... Departments of Medicinal Chemistry and Lead Discovery, X-Ceptor Therapeutics, Inc., 4757 Nexus Center Drive, San Diego, California 92121. ... While ERRα was the first orphan nuclear receptor identified over a decade ago, 11 the lack of a chemical tool has ...