Serotonin Inhibitors. II. 1 2'-(3-Dimethylaminopropylthio) cinnamanilide and Related Compounds

J Krapcho, ER Spitzmiller, CF Turk…

Index: Krapcho,J. et al. Journal of Medicinal Chemistry, 1964 , vol. 7, p. 376 - 377

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Citation Number: 6

Abstract

Table I1 were usually isolated by dilution of the cooled reaction mixture with anhydrous ether. Most of the other compounds of Table I1 were obtained by acylation of the amines listed in Table I, usually in yields exceeding SO%, with the appropriate acid chlorides. ... KO. 1 2 3 4 5 6 7 ... 8 9 10 11 12 14 15 16 17 18 ... 19k 20 21% 22 23' 24P 25 26 27 28 29 30' ... X S S S S S S S ... S S S S S so2 S S 0 0 0 ... 3 3 3 3 3 3 2 2 4 3 2