Vanadium-catalyzed cross-coupling reactions of alkyl halides with aryl Grignard reagents

S Yasuda, H Yorimitsu, K Oshima

Index: Yasuda, Shigeo; Yorimitsu, Hideki; Oshima, Koichiro Bulletin of the Chemical Society of Japan, 2008 , vol. 81, # 2 p. 287 - 290

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Citation Number: 19

Abstract

Vanadium (III) chloride catalyzed cross-coupling reactions of alkyl halides with arylmagnesium bromides. Various arylmagnesium bromides, except for an ortho-substituted arylmagnesium reagent, could be used for the reaction. Among alkyl halides tested, cyclohexyl halides and primary alkyl halides were good substrates. The reactions likely proceed via carbon-centered radical intermediates.