Combined Pd/C and Montmorillonite Catalysis for One??Pot Synthesis of Benzimidazoles

NA Weires, J Boster, J Magolan

Index: Weires, Nicholas A.; Boster, Jared; Magolan, Jakob European Journal of Organic Chemistry, 2012 , # 33 p. 6508 - 6512

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Citation Number: 9

Abstract

Abstract A series of nineteen benzimidazoles were prepared from ortho-nitroanilines by one- pot transfer hydrogenation, condensation, and dehydrogenation enabled by the concurrent use of two heterogeneous catalysts: montmorillonite-K10 and Pd/C. This strategy was further employed to accomplish a five-step, three-component synthesis of an antifungal benzimidazoquinazoline by using a simple one-pot procedure.