Alkylation of 5??and 6??Methylindolo [2, 3??b] quinoxalines: Revised Structures of the N, N′??Dimethylated Salts

…, S Desbène??Finck, S Giorgi??Renault

Index: Helissey, Philippe; Desbene-Finck, Stephanie; Giorgi-Renault, Sylviane European Journal of Organic Chemistry, 2005 , # 2 p. 410 - 415

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Citation Number: 6

Abstract

Abstract N, N′-Dialkylation of indolo [2, 3-b] quinoxaline could theoretically furnish three isomers, that is, salts dialkylated at the 5, 6-, the 6, 11-, and the 5, 11-positions. By using the 2, 3-dimethylated derivatives as models, the regioisomeric salts were selectively synthesized either by alkylation of the tetracycle or by cyclization of 1-methylisatin with N, 4, 5-trimethylbenzene-1, 2-diamine. The structure of the N, N′-dimethyl salts were ...