e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Tetrahedron

Direct alkylation of aromatics using alcohols in the presence of NaHSO 4/SiO 2

Y Sato, T Aoyama, T Takido, M Kodomari

Index: Sato, Yuta; Aoyama, Tadashi; Takido, Toshio; Kodomari, Mitsuo Tetrahedron, 2012 , vol. 68, # 35 p. 7077 - 7081

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Citation Number: 19

Abstract

Simple and efficient procedure for alkylation of aromatics from alcohols in the presence of NaHSO4/SiO2 was developed. Various triaryl methanes were obtained in good yields in short reaction time. For instance the reaction of mesitylene with benzhydrol in the presence of NaHSO4/SiO2 gave the corresponding triaryl methane in a quantitative yield. NaHSO4/SiO2 was regenerated by simple treatment and could be recycled eight times ...

Benzhydrol Structure

m-Xylene Structure

~99%

1-benzhydryl-2,4-dimethyl-benzene Structure

1-benzhydryl-2,...

Tritanol Structure

Anisole Structure

~87%

Triphenyl-p-anisylmethane Structure

Triphenyl-p-ani...

UNII:87652943HP Structure

UNII:87652943HP

~25%

dihydronaphthalene Structure

dihydronaphthalene

3-(1,2,3,4-tetrahydronaphthyl)-1,2-dihydronaphthalene Structure

3-(1,2,3,4-tetr...

1,2-Dimethoxybenzene Structure

1,2-Dimethoxybenzene

Benzyl alcohol Structure

~45%

4-benzyl-1,2-dimethoxybenzene Structure

4-benzyl-1,2-di...

1-benzyl-2,3-dimethoxybenzene Structure

1-benzyl-2,3-di...

4,4'-Dichlorobenzhydrol Structure

4,4'-Dichlorobe...

Chlorobenzene Structure

~27%

TRIS(4-CHLOROPHENYL)METHANE Structure

TRIS(4-CHLOROPH...

Anisole Structure

Bis(4-methoxyphenyl)methanol Structure

Bis(4-methoxyph...

~43%

1-[bis(4-methoxyphenyl)methyl]-4-methoxy-benzene Structure

1-[bis(4-methox...

Benzhydrol Structure

p-Xylene Structure

~97%

2-benzhydryl-1,4-dimethyl-benzene Structure

2-benzhydryl-1,...