Results In general, the reaction consists oi adding paraformaldehyde to a solution of a negatively substitutcd alcohol in concentrated sulfuric acid, at room temperature or below. The product begins to separate almost immediately, and only a small part of the total product remains dissolved in the reaction solution. After a reaction period of 1 hr or less, the acetal is isolated either directly from the reaction mixture by filtration, or by pouring the mixture onto ...
