e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedron letters
Synthesis and [3+ 2] cycloadditions of N-(trimethylsilylmethyl) isothioureas: a synthetic equivalent of novel 1, 3-dipolar reagent, iminoazomethine ylid
Abstract [3+ 2] cycloaddition; N-(trimethylsilylmethyl) isothiourea, synthetic equivalent; 1, 3- dipolar reagent, iminoazomethine ylid N-(Trimethylsilylmethyl) isothioureas, readily prepared by the reaction of N-bis (methylthio) methylene-cyanamide or-p- toluenesulfonamide with (trimethylsilylmethyl) amine, followed by N-alkylation, have been found to be a synthetic equivalent of iminoazomethine ylid. Treatment of these compounds ...