Scalable Total Synthesis of (−)??Berkelic Acid by Using a Protecting??Group??Free Strategy

FJ Fañanás, A Mendoza, T Arto…

Index: Fananas, Francisco J.; Mendoza, Abraham; Arto, Tamara; Temelli, Baris; Rodriguez, Felix Angewandte Chemie - International Edition, 2012 , vol. 51, # 20 p. 4930 - 4933

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Citation Number: 35

Abstract

Penicillium species obtained from the surface waters of Berkeley Pit Lake in Butte, Montana (USA).[1] This lake was formed when an abandoned copper mine was flooded with infiltrating ground water, thus resulting in the formation of a highly acidic (pH 2.5) and metal contaminated ecosystem where only extremophiles could survive. The microorganisms that tolerate these extreme growth conditions are a precious, although very scarce, source of ...