A Fast and Highly Efficient Protocol for Synthesis of Pyrrolo [2, 3-d] isoxazoles and a New Series of Novel Benzyl Bis-pyrrolo [2, 3-d] isoxazoles Using Task-Specific …

E Rajanarendar, S Raju, A Siva Rami Reddy…

Index: Rajanarendar, Eligeti; Raju, Samala; Siva Rami Reddy, Atthunuri; Govardhan Reddy, Kundur; Nagi Reddy, Modugu Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 6 p. 833 - 839

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Citation Number: 15

Abstract

We report a mild, fast, highly efficient and eco-friendly protocol for the green synthesis of pyrrolo [2, 3-d] isoxazoles and a new series of novel benzyl bis-pyrrolo [2, 3-d] isoxazoles from nitro styrylisoxazoles in SnCl 2-ionic liquid by reductive cyclization. These reactions were performed at ambient temperature which resulted in good yields in short reaction time, without requiring any organic solvent and catalyst.