A convenient preparation of γ-keto acids

A Takeda, K Takahasi, S Torii…

Index: Takeda,A. et al. Journal of Organic Chemistry, 1966 , vol. 31, p. 616 - 618

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Citation Number: 11

Abstract

2-Heptylidenesuccinic Acid (I, R= C&Ila).-3-Carbethoxy-3-decenoic acid, Stobbe half-ester (12 g, 0.05 mole), obtained by condensation of heptanal with diethyl succinate in the presence of potassum t-butoxide, E was hydrolyzed with 150 ml of 1 N aqueous alkaline solution at 8690'for 6-8 hr. The alkaline solution, after cooling to room temperature, was acidified with dilute sulfuric acid. The crude product was filtered and washed with 10 ml of ...