Journal of the American Chemical Society

Preparation of Secondary and Tertiary 2-Thiazolylamines

IA Kaye, CL Parris

Index: Kaye; Parris Journal of the American Chemical Society, 1952 , vol. 74, p. 2271

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Citation Number: 10

Abstract

In a recent patent2 there appeared a description of a method for the preparation, in low yield, of N, N-dimethyl-”-benzyl-”-(2-thiazolyl)-ethylenediamine (I). Since compounds of this type are of interest as chemotherapeutic agents, an investigation of some methods for the preparation of secondary and tertiary 2-thiazolylamines was initiated. Sondern and Breivoge12 prepared the diamine (I) by refluxing a mixture of 2-bromothiazole and N, N- ...