Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Synthetic hydroxydienone precursors to spiroleucettadine and to an isomer thereof resist cyclization to the orthoamide-type functionality present in the proposed structure of the natural product. ... In 2004, Crews and collaborators described a noteworthy marine alkaloid, which they ...